Since 2019, scientists and experienced proofreaders have utilized FlyWire to proofread AI segmentation of a full fly brain (Dorkenwald et al., Zheng et al.). As of April 2023, over 120,000 neurons have been proofread in FlyWire, including the entire central brain.
Automatically extracted presynaptic and postsynaptic tags have been applied to all putative connections in the brain (Buhmann et al.), and the dominant neurotransmitter assigned for most neurons (Eckstein et al.).
Explore the connectome and its annotations in Codex (FlyWire signup required). For programmatic analysis, see natverse (R) and CAVE (Python).
Community of neurobiologists, computer scientists, and proofreaders who build and curate the first whole brain connectome for Drosophila in FlyWire. Join FlyWire and contribute community data for your lab to appear.
Members adhere to a set of shared principles to join the community: FlyWire Data and Principles.
FlyWire is created by the labs of Mala Murthy and Sebastian Seung at Princeton University. It is funded by the US Brain Initiative. Proofreading and annotation has been carried out in collaboration with the Cambridge Drosophila Connectomics Group (funded by the Wellcome trust) and many other labs around the world.
Central Brain Proofreading Completion
Optic Lobes Proofreading Completion
Overall Proofreading Completion
Some cool 3D renderings